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Mounjaro is a weekly injectable medication prescribed for type 2 diabetes management that contains Tirzepatide and has been reported to aid with weight loss.

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What is Ketamine?

Ketamine is a medication primarily used for starting and maintaining anesthesia. It induces a trance-like state while providing pain relief, sedation, and memory loss. Other uses include for chronic pain, sedation in intensive care, and depression.

Ketamine is classified as a dissociative anesthetic, a type of drug that distorts perceptions of sight and sound and produces feelings of detachment from the environment and self. It’s known to have hallucinogenic and painkilling qualities.

Its mechanism of action involves blocking the NMDA (N-methyl-D-aspartate) receptor, a type of glutamate receptor in the brain, which results in analgesic, anesthetic, and psychotomimetic (psychosis-like) effects.

However, ketamine can be potentially abused due to its psychoactive properties. It can cause a range of side effects, such as confusion, hallucinations, increase in blood pressure, and potentially a serious respiratory issue if a patient has pre-existing breathing problems. It’s a controlled substance in many countries due to this potential for abuse and dependency.

As of my knowledge cutoff in September 2021, research is ongoing into the use of ketamine for treatment-resistant depression and certain other psychiatric disorders. Some promising results have been seen, but the long-term effects and optimal dosing strategies for these uses are still not entirely clear.

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Ketamine powder is a form of the drug ketamine that has been processed into a crystalline powder. This powder can be dissolved in liquids, snorted, or even smoked. It’s colorless and tasteless, which makes it difficult to detect when it’s been added to drinks, leading to its occasional use as a date rape drug.

Although ketamine has legitimate medical uses, the powder form is often associated with illicit use and is considered a controlled substance in many jurisdictions. It’s often sold on the street under various names such as “K,” “Special K,” “Kit Kat,” “Vitamin K,” or “Super Acid.”

Recreational users seek its hallucinogenic and dissociative effects. However, the misuse of ketamine can lead to serious health risks, including profound respiratory depression, heart problems, severe anxiety, and addiction.

It’s important to note that possession, distribution, or use of ketamine outside of prescribed medical use is often illegal and can result in serious legal consequences. Moreover, due to the unregulated nature of the street drug market, substances sold as “ketamine” may be adulterated with other harmful substances, posing further risks to the user.

Unveiling the Distinctions: R-Isomer Ketamine and S-Isomer Ketamine

Ketamine, a versatile anesthetic and analgesic medication, has gained significant attention due to its unique properties and potential therapeutic applications. Within the ketamine molecule, there exist two distinct isomers: R-isomer ketamine and S-isomer ketamine. These isomers possess subtle structural variations, resulting in divergent pharmacological effects and therapeutic potentials. In this essay, we will explore the characteristics, mechanisms of action, and potential applications of R-isomer ketamine and S-isomer ketamine, shedding light on their individual contributions to the field of medicine.

R-Isomer Ketamine:
R-isomer ketamine, also known as esketamine or S(+)-ketamine, is the enantiomer that exhibits a right-handed configuration. It has been extensively investigated for its anesthetic, analgesic, and antidepressant properties. R-ketamine primarily acts as a non-competitive antagonist of the N-Methyl-D-Aspartate (NMDA) receptor, binding to its phencyclidine (PCP) site. By blocking the NMDA receptor, R-ketamine interferes with the transmission of pain signals and modulates glutamate activity, leading to its analgesic effects. Furthermore, R-ketamine exhibits rapid onset and short duration of action, making it suitable for acute pain management and procedural sedation.

S-Isomer Ketamine:
Conversely, S-isomer ketamine, known as arketamine or R(-)-ketamine, represents the left-handed enantiomer. Its pharmacological properties differ from R-ketamine, as it exhibits a higher affinity for the opioid receptors, specifically the mu opioid receptor. By interacting with these receptors, S-ketamine produces potent analgesia and may offer potential benefits in the management of chronic pain. Additionally, S-ketamine modulates the release of norepinephrine and dopamine, leading to its antidepressant and psychomimetic effects. Its prolonged duration of action makes it suitable for sustained pain relief and treatment-resistant depression.

Therapeutic Applications:
The unique characteristics of R- and S-ketamine have paved the way for their distinct therapeutic applications. R-ketamine, in the form of ketamine nasal spray, has gained approval for the treatment of treatment-resistant depression, offering a promising alternative for patients who have not responded to conventional antidepressant medications. On the other hand, S-ketamine holds potential in the management of chronic pain, particularly neuropathic pain, where conventional analgesics may be ineffective. Ongoing research is exploring the use of S-ketamine as an adjunct to opioids in pain management protocols, aiming to enhance analgesic efficacy while minimizing opioid-related side effects.

R-isomer ketamine (esketamine) and S-isomer ketamine (arketamine) represent distinct entities within the ketamine molecule, each possessing unique pharmacological properties and therapeutic potentials. R-ketamine exhibits analgesic and antidepressant effects through NMDA receptor antagonism, whereas S-ketamine acts on opioid receptors, providing potent analgesia and potential antidepressant benefits. By understanding the different characteristics and mechanisms of action of these isomers, healthcare professionals can tailor their use to specific clinical contexts, maximizing their therapeutic benefits while minimizing adverse effects.

Although ketamine has legitimate medical uses, the powder form is often associated with illicit use and is considered a controlled substance in many jurisdictions. It’s often sold on the street under various names such as “K,” “Special K,” “Kit Kat,” “Vitamin K,” or “Super Acid.”

Recreational users seek its hallucinogenic and dissociative effects. However, the misuse of ketamine can lead to serious health risks, including profound respiratory depression, heart problems, severe anxiety, and addiction.

It’s important to note that possession, distribution, or use of ketamine outside of prescribed medical use is often illegal and can result in serious legal consequences. Moreover, due to the unregulated nature of the street drug market, substances sold as “ketamine” may be adulterated with other harmful substances, posing further risks to the user.


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How to Get Mounjaro in 2023

Mounjaro (tirzepatide) can help regulate blood sugar levels and reduce weight in people with type 2 diabetes. Doctors may also prescribe it off-label for obesity. It is available online with a prescription.

Mounjaro is a second-line treatment for type 2 diabetes, with doctors preferring metformin as a first-line treatment for high blood sugar levels.

Because Mounjaro can lead toTrusted Source significant weight loss, people with and without type 2 diabetes are keen to take it to lose weight. However, people should try Mounjaro for weight loss only if a doctor thinks it is appropriate.

There has been a shortage of Mounjaro in recent months due to its rise in popularity, and it is currently on the Food and Drug Administration (FDA) list of drug shortages. This means that people with diabetes have not been able to get the drug. However, all doses are currently available.

This article covers where people can order Mounjaro online, how to get a Mounjaro prescription from a doctor, and whether insurance will cover this drug. It also answers some frequently asked questions about Mounjaro.

Mounjaro for weight loss

People with diabetes rely on medications such as Mounjaro (tirzepatide) to regulate their blood sugar levels. This drug does not have FDA approval for weight loss.

However, the FDA has approvedTrusted Source Wegovy (semaglutide) specifically for weight loss. People may wish to consider choosing Wegovy over Mounjaro. These medications should be used alongside a balanced diet and exercise for weight loss.

What is Mounjaro for?

Mounjaro is an injectable brand-name medication that contains tirzepatide. It is a glucagon-like peptide 1 (GLP-1) receptor agonist and a gastric inhibitory polypeptide (GIP) agonist.

As a GLP-1 agonist, it mimics a hormone called GLP-1, helps boost insulin production, when necessary, reduces sugar production in the liver, and slows down food digestion.

As a GIP agonist, it encourages insulin production and sensitivity and reduces the production of stomach acid. This means food will digest more slowly.

This dual action makes it a unique medication in its market.

How quickly do you lose weight on Mounjaro?
How quickly do you lose weight on Mounjaro?

It has FDA approvalTrusted Source as a treatment for type 2 diabetes, but doctors may also prescribeTrusted Source it off-label for people with obesity. “Off-label” means a doctor prescribes a drug for a condition or at a dosage that the FDA has not approved, but only when appropriate.

Doctors prescribe Mounjaro to treat obesity because it slows digestion and can reduce a person’s appetite.

While Mounjaro does not currently have approval as a weight loss drug, the FDA has fast-trackedTrusted Source it for approval, and its manufacturer is submitting clinical tests to support its application. This means Mounjaro may become FDA-approved for weight loss in 2023.

The manufacturer, Eli Lilly and Company, will use data showing that Mounjaro led to a 15% reduction in body weight as part of its application for approva

Where can you get Mounjaro online?

Several telehealth companies offer Mounjaro. Read about five of the best options below.

Please note that the writer of this article has not tried these products. All information presented is purely research-based and correct at the time of publication.

Medical News Today follows a strict product selection and vetting process. 

Best for health insurance coverage: Sesame Care

  • Branded or generic: generic
  • Appointment cost: varies by doctor.
  • Accepts insurance: yes.

Sesame Care is a telehealth company that offers in-person and virtual doctor visits, prescription refills, and same-day medication pickup from pharmacies.

People can get tirzepatide, the generic version of Mounjaro, from Sesame Care. The company does not specify whether its doctors will prescribe the drug off-label for weight loss.

First, a person must book an appointment with a Sesame healthcare professional. If the healthcare professional thinks it is appropriate, they will prescribe tirzepatide. The cost of these appointments will vary by doctor.

Afterward, the customer can collect their order from a local pharmacy.

People can use a health savings account (HSA), a flexible spending account (FSA), or health insurance to pay for Sesame Care’s services. It is also open to those without health insurance.

How to get Mounjaro without insurance

People without insurance can get Mounjaro, but it may be more expensive. Lilly, Mounjaro’s manufacturer, states that the drug’s list price is $1,023.04 for a month’s supply. This is the price Lilly sets for wholesalers buying Mounjaro, and the pharmacy price that customers will pay may differ from this.

Lilly does not provide its savings card to people who do not have insurance or to those who use state, federal, or government healthcare programs such as Medicaid, Medicare, Medicare Part D, Medicare Advantage, and Medigap.

People should read the terms on Lilly’s website to see whether they are eligible to save on Mounjaro.

What Mounjaro costs

The cost of a prescription drug can vary widely in the United States, and people often look for ways to save on prescription medication.

With insurance, some people will be eligible for Lilly’s Mounjaro Savings Card, which costs $25 for a 1- or 3-month prescription. A 1-month supply includes 4 pens across 28 days. A 3-month supply includes up to 12 pens for 84 days.

Those with insurance that does not cover Mounjaro can still use the Mounjaro Savings Card for up to $575 off a 1-month prescription. However, they will still likely need to pay a few hundred dollars for Mounjaro.

It is also important to note that the Mounjaro Savings Card program will end on December 31, 2023.

Lilly writes that people without insurance may pay close to the list price of Mounjaro, which is $1,023.04 for 4 pens.

Through GoodRx, people can get Mounjaro for around $990, depending on the pharmacy.

Learn more about the cost of Mounjaro.

How to save money on Mounjaro

Individuals who use Mounjaro long term may consider buying 90-day supplies to save money. They may discuss their options with a pharmacist or doctor.

The Mounjaro Savings Card also dramatically reduces the cost of the drug.

What to ask the doctor about Mounjaro

People wanting to discuss Mounjaro with a doctor may wonder what questions they should ask during their appointment. Below, we list several important points to talk about with a doctor before getting a Mounjaro prescription:

  • Does Mounjaro interact with other medications?
  • What side effects does it cause?
  • Will it interact with my diabetes medication?
  • What makes it different from other GLP-1 medications?
  • How do I take Mounjaro?
Frequently asked questions about Mounjaro

Below, we answer some frequently asked questions about Mounjaro.

Do you need a prescription for tirzepatide?

Yes, people will need a prescription for tirzepatide.

How can I get Mounjaro for weight loss?

To get Mounjaro for weight loss, a person should speak with a doctor in person or online via a telehealth company. The doctor will decide whether Mounjaro is appropriate for the person’s health goals.

Where can you get Mounjaro?

People can get Mounjaro from a pharmacy if they have a valid prescription. People can get a prescription by visiting a doctor’s office or using a telehealth platform.

How can you get Mounjaro covered by insurance?

Many insurance companies will cover Mounjaro only for FDA-approved uses, such as treating type 2 diabetes. A person’s insurance provider may require prior authorization for Mounjaro before it approves a person’s claim. This means a doctor will have to tell a person’s insurance company that Mounjaro is medically necessary. This can take several days.

Those without type 2 diabetes who want Mounjaro for weight loss may not be able to get insurance coverage.

People should contact their insurance provider to see whether their plan will cover Mounjaro.


Mounjaro is a prescription GLP-1 agonist medication that the FDA has approved to treat type 2 diabetes. Medical professionals may also prescribe it off-label for weight loss in people with obesity.

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